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Principle of muscle contraction caused by nerve stimulation

The process of muscle contraction caused by nerve stimulation is conducted along the motor nerve and transmitted to muscle cells. This process is called nerve muscle excitation transmission. The action potential on the surface of muscle cell membrane is transmitted to the interior of muscle cell through the triple tube structure of muscle cell, which triggers information transmission. Calcium ions are released from the sarcoplasmic reticulum to the sarcoplasmic reticulum and transfer information to the internal regulatory proteins of the sarcoplasmic reticulum, which is called excitation contraction coupling.

After that, the high concentration of calcium ions in the sarcoplasma triggers the binding of contractile proteins through the regulatory proteins in the sarcoplasma, so as to achieve the purpose of muscle contraction. In fact, the principle of muscle contraction caused by nerve stimulation is a contraction process from electrical signal to chemical signal.

Spinal cord electrical stimulation is commonly used to treat postoperative pain syndrome, phantom limb pain, central pain and distal pain caused by lumbar and thoracic injury. Spinal cord electrical stimulation is expensive, and patients need to have a certain economic foundation. This treatment method is not widely used in grass-roots hospitals in China. If the treatment can reduce the pain of patients by more than 50%, it is considered effective in clinic. It should be noted that the electric stimulation pump may be damaged if it is applied for a long time. Patients should be psychologically prepared.

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